Process for preparing...

Details Process for preparing... Process for preparing...

C - Chemistry, Metallurgy

07

D

C07D 471/04 (2006.01)

Patent

CA 2541477

Starting from ethyl 3-(2,6-dichloro-5-fluoropyridin-3-yl)-3-oxo-propanoate (1), the present invention provides highly pure 7-chloro-1-cyclopropyl-6- fluoro-4-oxo-1,4-dihydro-1,8-naphthyridine-3-carboxylic acid (5) inone-potfour stepsusing a single solvent.

La présente invention permet d'obtenir, à partir d'éthyl 3-(2,6-dichloro-5-fluoropyridin-3-yl)-3-oxo-propanoate (1), un acide 7-chloro-1-cyclopropyl-6-fluoro-4-oxo-1,4-dihydro-1,8-naphthyridine-3-carboxylique (5) dans un seul appareil et en quatre opérations en utilisant un seul solvant.

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