C - Chemistry – Metallurgy – 07 – C
Patent
C - Chemistry, Metallurgy
07
C
C07C 51/09 (2006.01) C07C 59/68 (2006.01) C07C 69/63 (2006.01) C07C 69/712 (2006.01) C07C 219/06 (2006.01) C07D 295/15 (2006.01)
Patent
CA 2042304
PROCESS FOR THE PREPARATION OF 2,2-DIMETHYL-5-(2,5-DIMETHYL PHENOXY)-PENTANOIC ACID, INTERMEDIATES FOR PREPARING THIS COMPOUND AND PROCESS FOR PREPARING THE INTERMEDIATES ABSTRACT The invention relates to an improved process for the preparation of 2,2-dimethyl-5-(2,5-dimethylphenoxy)-pentanoic acid of Formula (I) Image (I) which comprises reacting an ester of the general Formula (X) (X) Image - wherein X represents halogen and Z stands for a straight or branched chain C1-8 alkylene group optionally substituted by one or two 2,2-dimethyl-5-halopentanoyloxy group(s), wherein halo represents chlorine or bromine, and in which alkylene group one or two methylene group(s) may be optionally replaced either by hetero atom(s) or by a bivalent heterocyclic group - with an alkali salt of 2,5-dimethylphenol of Formula (II) (II) Image - 2 - or with an ester of the latter formed with a lower alkanoic acid, and hydrolizing the aryloxy-substituted ester of the general Formula (XI) thus obtained. Image (XI) Furthermore the invention relates to intermediate compounds of the general Formula (X), wherein X and Z are as stated above, and to a process for the preparation thereof.
Feher Gabor
Kovacs Gabor
Krasznai Gyorgy
Moravcsik Imre
Nagy Kalman
Egis Gyogyszergyar Rt.
G. Ronald Bell & Associates
LandOfFree
Process for preparing... does not yet have a rating. At this time, there are no reviews or comments for this patent.
If you have personal experience with Process for preparing..., we encourage you to share that experience with our LandOfFree.com community. Your opinion is very important and Process for preparing... will most certainly appreciate the feedback.
Profile ID: LFCA-PAI-O-1922983