Process for preparing...

Details Process for preparing... Process for preparing...

C - Chemistry, Metallurgy

07

D

C07D 207/327 (2006.01) C07D 207/00 (2006.01) C07D 309/00 (2006.01) C07D 405/06 (2006.01)

Patent

CA 2521903

A method for preparing 5-(4-fluorophenyl)-1-[2R,4R)-4- hydroxy-6-oxo- tetrahydro-pyran-2-yl)ethyl]-2-isopropyl-4-phenyl-1H-pyrrole-3-carboxylic acid phenylamide (I), a key intermediate in the synthesis of atorvastatin calcium, is described.

L'invention porte sur un procédé de préparation de phénylamide (I) d'acide carboxylique 5-(4-fluorophényl)-1-[2-((2R,4R)-4-hydroxy-6-oxo-tétrahydro-pyran-2-yl)-éthyl]-2-isopropyl-4-phényl-1H-pyrrole-3, un intermédiaire clé dans la synthèse du calcium d'atorvastatine.

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