C - Chemistry – Metallurgy – 07 – D
Patent
C - Chemistry, Metallurgy
07
D
260/299, 260/305
C07D 519/00 (2006.01) C07D 231/04 (2006.01) C07D 477/20 (2006.01) C07D 487/04 (2006.01)
Patent
CA 2033479
Novel and improved simple process for preparing carbapenem compound, (1R,5S,6S)-2-((6,7-dihydro-5H- pyrazolo (1,2-a](1,2,4]triazolium-6-yl)]thio-6-((R)-1- hydroxyethyl]-1-methyl-carbapenem-3-carboxylate represented by the following formula: Image This compound may be prepared by using a mercapto reagent, 6,7-dihydro-6-mercapto-5H-pyrazolo- (1,2-a](1,2,4]triazolium derivative of the following formula: Image wherein X~ is an anion charge.
Abe Takao
Nagase Yunosuke
Tamai Satoshi
Lederle (japan) Ltd.
Smart & Biggar
Wyeth K.k.
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