Process for preparing 17-allyl amino geldanamycin (17-aag)...

Details Process for preparing 17-allyl amino geldanamycin (17-aag)... Process for preparing 17-allyl amino geldanamycin (17-aag)...

C - Chemistry, Metallurgy

07

D

C07D 225/06 (2006.01) A61K 31/395 (2006.01) C07D 498/22 (2006.01)

Patent

CA 2460498

Efficient chemical processes for preparing high yields, purities, and different polymorphic forms of 17-allyl amino geldanamycin (17-AAG) and other ansamycins are described and claimed.

La présente invention concerne des procédés chimiques efficaces de préparation à haut rendement de 17-allyl amino geldanamycine (17-AAG) de grande pureté et de formes polymorphes de ces dernières ainsi que d'autres ansamycines.

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