Process for preparing 2-acyl-3,4-dialkoxyanilines

C - Chemistry – Metallurgy – 07 – D

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260/557, 260/579

C07D 265/22 (2006.01) C07D 239/74 (2006.01)

Patent

CA 1269979

ABSTRACT A process for preparing 2-acyl-3,4-dialkoxy- anilines is described. The 2-acyl-3,4-dialkoxyanilines are useful intermediates in the preparation of 5,6- dialkoxy-4-alkyl-2(1H)-quinazolinones. The substituted quinazolinones are active as cardiotonic agents. The 2-acyl-3,4-dialkoxyanilines have the following formula: Image wherein R1, R2 and R3 are lower alkyl having 1-5 carbon atoms and R2 and R3 when taken together are methylenedioxy.

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