Process for preparing 2-keto-l-gulonic acid

Details Process for preparing 2-keto-l-gulonic acid Process for preparing 2-keto-l-gulonic acid

C - Chemistry, Metallurgy

12

P

195/34.8

C12P 7/60 (2006.01) C12N 1/20 (2006.01)

Patent

CA 1200220

Abstract of the Disclosure Fermentative or enzymatic production of 2-keto- L-gulonic acid from 2,5-diketo-D-gluconic acid using living or processed mutants, being defective in metabolizing 5- keto-D-gluconic acid and incapable of producing 2-keto-D- gluconic acid, is disclosed. The mutant is derived from 2-keto-L-gluconic acid producing microorganisms of genus Corynebacterium. The production is carried out in the presence of nitrates and/or hydrogen donors in a preliminarily sterilized fermentation broth in which a 2,5-diketo-D- gluconic acid producing microorganism of genus Gluconobacter or Erwinia has been cultivated. - 49 -

422970

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