Process for preparing 3-[4-(4-aryl-1-piperidyl)-...

Details Process for preparing 3-[4-(4-aryl-1-piperidyl)-... Process for preparing 3-[4-(4-aryl-1-piperidyl)-...

C - Chemistry, Metallurgy

07

D

260/279, 260/279

C07D 401/06 (2006.01) C07D 209/14 (2006.01)

Patent

CA 1133484

ABSTRACT OF THE DISCLOSURE Indolealkylamines of the formula Image wherein Ind is 1-R4-2-R5-indol-3-yl or the corresponding group in which the benzene ring is monosubstituted to tri- substituted by alkyl, O-alkyl, S-alkyl, OH, F, C1, Br, CF3 or CN; A is -(CH2)4-, -(CH2)3-CO- or -CO-(CH2)2-CO; R1 is H or methyl; R2 is H or together with R3 is a C-C bond; R3 is H or together with R2 is a C-C bond; R4 and R5 are each H, alkyl, or phenyl; and Ar is phenyl or phenyl monosubstituted or disubstituted by alkyl, F, Cl, Br, I or CF3; wherein alkyl in each case is of 1-4 carbon atoms; and the physiologically acceptable acid addition salts thereof possess valuable pharmacological properties.

330427

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