C - Chemistry – Metallurgy – 07 – D
Patent
C - Chemistry, Metallurgy
07
D
260/253, 260/242
C07D 239/78 (2006.01) C07D 239/82 (2006.01)
Patent
CA 1049521
A NOVEL PROCESS FOR PREPARING 3,4-DIHYDRO-2(1H)-QUINAZOLINONE DERIVATIVES ABSTRACT OF THE DISCLOSURE 3,4-Dihydro-2(1H)-quinazolinones and quniazolinethiones such as 1-cyclopropylmethyl-4-phenyl- 6-methoxy-3,4-dihydro-2(1H)-quinazolinone and its thione derivative, are prepared in high yield with high purity by heating the corresponding arylurea or thiourea such as N-cyclopropylmethyl-N-(p-methoxyphenyl) urea or its thiourea derivative, with the corresponding aldehyde such as benzaldehyde in the presence of hydrobromic acid in an inert solvent.
263980
Katayama Shigenari
Koshiba Masao
Yamamoto Hisao
Yamamoto Michihiro
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