Process for preparing 3, 4-disubstituted phenylacetic acids...

Details Process for preparing 3, 4-disubstituted phenylacetic acids... Process for preparing 3, 4-disubstituted phenylacetic acids...

C - Chemistry, Metallurgy

07

C

C07C 327/44 (2006.01) A01N 37/34 (2006.01) A01N 37/38 (2006.01) A61K 31/16 (2006.01) A61K 31/277 (2006.01) C07C 315/00 (2006.01) C07C 319/14 (2006.01) C07C 323/62 (2006.01)

Patent

CA 2640126

A process for preparing 3,4-disubstituted phenylacetic acids of the formula (I) in which X is fluorine, chlorine, bromine or iodine and R is C1-C4- alkylthio, C1-C4-alkylsulfonyl or C1-C4-alkylsulfoxide, starting from a 2-halo- C1-C4-alkylthiobenzene of the formula (II) in which X is as defined above and R1 is C1-C4-alkylthio.

La présente invention concerne un procédé de synthèse d'acides phénylacétiques 3,4-disubstitués de formule (I), dans laquelle X représente fluor, chlore, brome ou iode et R représente un groupement alkylthio en C1-C4, alkylsulfonyle en C1-C4 ou alkylsulfoxyde en C1-C4, en partant d'un 2-halogéno-(alkyle en C1-C4)thiobenzène de formule (II), X étant tel que défini ci-avant et R1 représentant un groupement alkylthio en C1-C4.

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