Process for preparing 3-aminothienopyridone derivatives

Details Process for preparing 3-aminothienopyridone derivatives Process for preparing 3-aminothienopyridone derivatives

C - Chemistry, Metallurgy

07

D

C07D 495/04 (2006.01) C07D 211/90 (2006.01)

Patent

CA 2528927

This invention provides a class of 3-amino-7H-thieno[2,3-b]pyridin-6-one derivatives, substituted in the 7-position by an aryl, heteroaryl, cycloalkyl or heterocycloalkyl moiety, and in the 2-position by a specified range of substituent groups; also provided is a process for preparing those compounds, and the use thereof as intermediates in the manufacture of certain p38 MAP kinase inhibitors.

L'invention concerne une catégorie de dérivés de 3-amino-7<I>H</I>-thiéno[2,3-<i>b</i>]pyridin-6-one substitués en position 7 par une fraction aryle, hétéroaryle, cycloalkyle ou hétérocycloalkyle et, en position 2, par une plage spécifique de groupes substituants. Elle concerne également un procédé servant à préparer ces composés, ainsi que leur utilisation en tant qu'intermédiaires dans la préparation de certains inhibiteurs de p38 MAP kinase.

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