Process for preparing 3-arylsulfur hydroxamic acids

Details Process for preparing 3-arylsulfur hydroxamic acids Process for preparing 3-arylsulfur hydroxamic acids

C - Chemistry, Metallurgy

07

D

C07D 309/08 (2006.01) C07C 317/44 (2006.01) C07C 319/14 (2006.01) C07C 319/20 (2006.01) C07C 323/09 (2006.01) C07C 323/20 (2006.01) C07C 323/60 (2006.01) C07D 207/16 (2006.01) C07D 211/62 (2006.01) C07D 265/30 (2006.01) C07D 279/12 (2006.01)

Patent

CA 2274375

This invention provides processes for the preparation of a compound of formula I: Y-C(=O)-C(R1)(R2)-CH2-S(O)nR3 wherein: Y is hydroxy or XONX, where each X is independently hydrogen, lower alkyl or lower acyl; R1 is hydrogen or lower alkyl; R2 is hydrogen, lower alkyl, aryl, aralkyl, cycloalkyl, cycloalkylalkyl, or R1 and R2 together with the carbon atom to which they are attached form a cycloalkyl or heterocyclo group; and R3 is aryl. The invention also provides novel aryl haloalkyl sulfide and aryl alkyl sulfide intermediates useful for the preparation of compounds of formula I and novel processes of preparing aryl alkyl sulfides.

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