Process for preparing 3-chloro-1,2-propanediol

Details Process for preparing 3-chloro-1,2-propanediol Process for preparing 3-chloro-1,2-propanediol

C - Chemistry, Metallurgy

12

P

195/129, 195/65

C12P 41/00 (2006.01)

Patent

CA 1338723

A process for preparing an optically active 3- chloro-1,2-propanediol by employing microorganism which can selectively metabolize (R)- or (S)-3-chloro-1,2- propanediol. The decomposition rate of the substrate can be accelerated and the substrate concentration can be increased by adding a compound having SH group to the reaction solution. According to the process of the present invention, the optically active 3-chloro-1,2-propanediol can be easily prepared starting from low-cost (R,S)-3- chloro-1,2-propanediol.

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