Process for preparing 3-(pyrid-4-yl)propanoic acid derivatives

Details Process for preparing 3-(pyrid-4-yl)propanoic acid derivatives Process for preparing 3-(pyrid-4-yl)propanoic acid derivatives

C - Chemistry, Metallurgy

07

D

260/296

C07D 213/64 (2006.01)

Patent

CA 1265143

11833 A B S T R A C T A process for preparing compounds of the formula (II): Image (II) and salts thereof, wherein R1 is protected hydroxy, which comprises reacting an anion of the formula (III) : Image (III) wherein R1 is as hereinbefore defined, with a compound of the formula (IV) : X-CH2C0?M+ wherein X is a leaving group and M is a counterion, and if desired interconverting an acid of the formula (II) with a salt thereof. The products are intermediates in the preparation of histamine antagonists.

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