Process for preparing...

Details Process for preparing... Process for preparing...

C - Chemistry, Metallurgy

07

D

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C07D 501/20 (2006.01) A61K 31/545 (2006.01) C07D 205/08 (2006.01) C07D 233/54 (2006.01) C07D 257/04 (2006.01) C07D 261/06 (2006.01) C07D 279/06 (2006.01) C07D 285/04 (2006.01) C07D 333/04 (2006.01) C07D 501/02 (2006.01) C07D 501/04 (2006.01) C07D 501/26 (2006.01) C07D 501/30 (2006.01) C07D 501/34 (2006.01) C07D 501/36 (2006.01) C07D 501/42 (2006.01) C07D 501/46 (2006.01) C07D 501/48 (2006.01) C07D 501/52 (2006.01) C07D 501/56 (2006.01) C07D 501/57 (2006.01) C07D 501/60 (2006.01)

Patent

CA 1065304

ABSTRACT 7.beta.-Acylamino-7.alpha.-alkoxycephalosporins, which are useful antibacterial agents, are prepared by reacting a 7-acylaminocephalosporin with a halogenating agent to give the corresponding imino halide, reacting this imino halide with a base to give a keteneimine, reacting the keteneimine with a halogen to give an .alpha.-haloimino halide, reacting the .alpha.-haloimino halide with an alkali metal alkoxide, and finally either reacting the resulting compound with an acid or a halogen-substituted silane and treating the resulting compound with water, or hydrolysing the product of the reaction between the alkali metal alkoxide and the .alpha.-haloimino halide.

233673

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