Process for preparing 4h-1,2,4-triazole derivatives

Details Process for preparing 4h-1,2,4-triazole derivatives Process for preparing 4h-1,2,4-triazole derivatives

C - Chemistry, Metallurgy

07

D

260/313.3, 260/3

C07D 249/08 (2006.01) C07D 405/00 (2006.01)

Patent

CA 1256113

PRECIS DE LA DIVULGATION: L'invention concerne un nouveau procédé de préparation des composes de formule (I): Image (I) dans laquelle R1, R2, R3 et R4 représentent H, OH, alcoyle (1-4C), alcoxy (1-4C),-NH2, -NHalc2, Image halogène,-CF3,-NO2 ou R1 et R2 et/ou R3 et R4 forment un radical méthylènedioxy, R représente un alcoyle (1-4C), -CHOH-alc4 ou - Image , alc2, alc3, alc'3, alc4 et alc5 sont alcoyles (1-4C), sous leurs formes racémiques ou optiquement actives, ainsi que de leurs sels d'addition avec les acides. L'invention concerne notamment des triazoles de formule (I) dans laquelle R =-CHOH-alc4 ou - Image qui sont nouveaux. Ceux-ci sont utiles comme médicamments.

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