Process for preparing 5,6-substituted-2, 4-...

Details Process for preparing 5,6-substituted-2, 4-... Process for preparing 5,6-substituted-2, 4-...

C - Chemistry, Metallurgy

07

C

260/558.1

C07C 255/58 (2006.01) C07C 255/00 (2006.01) C07D 239/00 (2006.01) C07D 239/84 (2006.01) C07D 239/94 (2006.01) C07D 239/95 (2006.01)

Patent

CA 1282078

P3-3533 Abstract An improved process for the preparation of 6-sub- stituted-5-alkyl)-2,4-quinazolinediamines, useful in the production of trimetrexate and similar antifolate agents, together with several novel intermediates are disclosed.

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