Process for preparing...

Details Process for preparing... Process for preparing...

C - Chemistry, Metallurgy

07

D

C07D 405/06 (2006.01)

Patent

CA 2494269

A method for preparing 5-(4-fluorophenyl)-I-[2-((2R, 4R)-4-hydroxy-6-oxo- tetrahydro-pyran-2-yl)-ethyl]-2-isopropyl-4-phenyl-1H-pyrrole-3-carboxylic acid phenylamide (I), a key intermediate in the synthesis of atorvastatin calcium, is described.

L'invention concerne un procédé de préparation de phénylamide (I) d'acide carboxylique 5-(4-fluorophényl)-I-[2-((2R,4R)-4-hydroxy-6-oxo-tétrahydro-pyran-2-yl)-éthyl]-2-isopropyl-4-phényl-1<I>H</I>-pyrrole-3, un intermédiaire clé dans la synthèse du calcium d'atorvastatine.

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