Process for preparing a polymorph of rosiglitazone maleate

C - Chemistry – Metallurgy – 07 – D

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C07D 417/12 (2006.01)

Patent

CA 2520249

A crystallisation process for preparing a polymorph of rosiglitazone maleate (Compound 1), and a process for preparing Compound 1 with a polymorphic purity that is suitable for use as a seed material in a crystallisation process for preparing Compound 1.

L'invention concerne un procédé de cristallisation pour préparer un polymorphe de maléate de rosiglitazone (composé 1), et un procédé de préparation du composé 1 présentant une pureté polymorphique appropriée à une utilisation en tant que matériau de germe dans un procédé de cristallisation destiné à préparer le composé 1.

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