Process for preparing a solid dosage form

Details Process for preparing a solid dosage form Process for preparing a solid dosage form

A - Human Necessities

61

K

A61K 9/16 (2006.01) A61K 9/20 (2006.01)

Patent

CA 2655958

This invention provides a process for preparing a solid dosage form, comprising: preparing an aqueous slurry, solution or suspension of (a) a powder material, and (b) a mixture of one or more polyols and one or more maltodextrins, and spray drying the resultant aqueous slurry, solution or suspension, thereby obtaining particles which are directly compressible into a solid dosage form being able to disintegrate in an aqueous medium within no more than 15 minutes.

La présente invention concerne un procédé d'élaboration d'une forme galénique solide, ledit procédé comprenant : - l'élaboration d'une boue, d'une solution ou d'une suspension aqueuse de (a) une substance en poudre, et de (b) un mélange d'un ou de plusieurs polyols et d'une ou de plusieurs maltodextrines, et - le séchage par atomisation de la boue, solution ou suspension aqueuse résultante ce qui permet d'obtenir des particules directement compressibles en une forme galénique solide capable de se désintégrer dans un milieu aqueux en moins de 15 minutes.

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