C - Chemistry – Metallurgy – 07 – D
Patent
C - Chemistry, Metallurgy
07
D
C07D 471/04 (2006.01) C07D 213/803 (2006.01) C07D 213/82 (2006.01)
Patent
CA 2419764
The present invention provides a new process for large-scale preparation of substituted imidazopyridine compound of formula (I) wherein R1 is C1-C6 alkoxy or NH2 group, comprising the step of reacting a compound of formula (2) with a 3-halo-2-butanone compound in cyclohexanone.
La présente invention concerne un nouveau procédé pour préparer en grande quantité un composé d'imidazopyridine substitué de formule (I) dans laquelle R?1¿ est un alcoxy C¿1?-C¿6? ou un groupe NH¿2?, ce procédé consistant notamment à faire réagir un composé de formule (2) avec un composé 3-halo-2-butanone dans de la cyclohexanone.
Elman Bjorn
Erback Silke
Thiemermann Eric
Astrazeneca Ab
Fetherstonhaugh & Co.
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