Process for preparing acyclic hcv protease inhibitors

Details Process for preparing acyclic hcv protease inhibitors Process for preparing acyclic hcv protease inhibitors

C - Chemistry, Metallurgy

07

K

C07K 5/08 (2006.01) C07C 217/84 (2006.01) C07D 277/56 (2006.01) C07D 417/04 (2006.01) C07D 417/14 (2006.01)

Patent

CA 2568008

Disclosed are highly convergent processes for preparing compounds of formula (I), which compounds are potent active agents for the treatment of hepatitis C virus (HCV) infection. The disclosed processes use SNAr-type coupling reactions between peptidic compounds having a hydroxyproline moiety and halogenated or sulfonated bromoquinoline compounds.

La présente invention concerne des processus hautement convergents de préparation de composés représentés par la formule (I), ces composés étant des agents actifs puissants destinés au traitement d'une infection par le virus de l'hépatite C (VHC). Des processus de cette invention utilisent des réactions de couplage de type S<SB>N</SB>Ar entre des composés peptidiques possédant une fraction hydroxyproline et des composés bromoquinoline halogénés ou sulfonés.

Affiliated with

Also associated with

Rating

Process for preparing acyclic hcv protease inhibitors does not yet have a rating. At this time, there are no reviews or comments for this patent.

If you have personal experience with Process for preparing acyclic hcv protease inhibitors, we encourage you to share that experience with our LandOfFree.com community. Your opinion is very important and Process for preparing acyclic hcv protease inhibitors will most certainly appreciate the feedback.

Rate now

Comments { 0 }

Profile ID: LFCA-PAI-O-1899754