Process for preparing acylphosphanes and derivatives thereof

Details Process for preparing acylphosphanes and derivatives thereof Process for preparing acylphosphanes and derivatives thereof

C - Chemistry, Metallurgy

07

F

C07F 9/50 (2006.01)

Patent

CA 2531318

The present invention relates to a new, selective process for the preparation of mono- and bisacylphosphanes of formula (I) n and m are each independently of the other 1 or 2; R1, if n = 1, is e.g. phenyl R1, if n = 2, is e.g. C1- C18alkylene or phenylene; R2 is e. g. C1-C18alkyl, phenyl or substituted phenyl; R3 is e. g. C1-C18alkyl, by (1) reacting a phosphorous halide of formula Ila or a phosphorous halide oxide of formula (Ilb) or a phosphorous halide sulfide of formula (IIc) with an alkali metal in a solvent in the presence of a proton source; (2) subsequent reaction with m acid halides of formula (III) An oxidation step may follow to obtain mono- and bisacylphosphane oxides or mono-and bisacylphosphane sulfides.

La présente invention concerne un nouveau procédé sélectif permettant la préparation de mono- et bisacylphosphanes de formule (I), dans laquelle n et m représentent indépendamment 1 ou 2 ; R¿1? désigne p. ex. phényle, si n = 1 ; R¿1? désigne p. ex. phénylène ou alkylène en C¿1?-C¿18?, si n = 2 ; R¿2? désigne p. ex. alkyle en C¿1?-C¿18?, phényle ou phényle substitué ; R¿3? désigne p. ex. alkyle en C¿1?-C¿18?, lequel procédé consiste (1) à faire réagir un halogénure de phosphore de formule (Ila) ou un oxyde d'halogénure de phosphore de formule (Ilb) ou un sulfure d'halogénure de phosphore de formule (IIc) avec un métal alcalin dans un solvant en présence d'une source de protons puis (2) à mettre en oeuvre une réaction consécutive au moyen de m halogénures d'acide de formule (III). Une étape d'oxydation éventuelle permet, par la suite, d'obtenir des oxydes de mono- et bisacylphosphane ou des sulfures de mono- et bisacylphosphane.

Affiliated with

Also associated with

Rating

Process for preparing acylphosphanes and derivatives thereof does not yet have a rating. At this time, there are no reviews or comments for this patent.

If you have personal experience with Process for preparing acylphosphanes and derivatives thereof, we encourage you to share that experience with our LandOfFree.com community. Your opinion is very important and Process for preparing acylphosphanes and derivatives thereof will most certainly appreciate the feedback.

Rate now

Comments { 0 }

Profile ID: LFCA-PAI-O-1514212