Process for preparing alkylenediamine derivatives

C - Chemistry – Metallurgy – 07 – D

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C07D 239/84 (2006.01) C07D 239/95 (2006.01) C07D 307/24 (2006.01) C07D 407/12 (2006.01)

Patent

CA 1102330

A B S T R A C T "PROCESS FOR PREPARING ALKYLENEDIAMINE DERIVATIVES" A process for preparing alkylenediamine amides corres- ponding to the general formula (I) Image (I) in which R1 and R2 each represent, independently of one another, a hydrogen atom, an alkyl having 1 to 4 carbon atoms or the benzyl radical, n is equal to 3 and R represents either a cycloalkyl radical having 3 to 6 carbon atoms, or a radical Image , in which m is 0, 1 or 2, or a radical Image or Image , or a radical Image , in which m is 0, 1 or 2 and p is 0, 1 or 2, and also their addition salts with pharmaceutically acceptable acids, by reacting an aminoamide Image with a 4-amino-2- halogeno-6,7-dimethoxyquinazoline (II). The compounds are useful in treating cardiovascular disorders.

320864

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