Process for preparing aloe-emodin

C - Chemistry – Metallurgy – 07 – C

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Details

C07C 51/27 (2006.01) C07C 66/02 (2006.01) C07C 67/08 (2006.01) C07C 69/16 (2006.01)

Patent

CA 2586260

A process for preparing aloe-emodin from aloin by oxidizing aloin by treatment with an oxygen-containing gas in the presence of an acid. The aloe-emodin may be used for the production of rhein and diacerein by oxidizing aloe-emodin by treatment with a chromium-free oxidizing medium to obtain rhein and purifying the rhein obtained. The rhein may be acetylated to obtain diacerein.

La présente invention concerne un procédé d'élaboration d'aloé-émodine en partant d'aloïne que l'on oxyde en présence d'acide au moyen d'un gaz oxygéné. A son tour, l'aloé-émodine convient à la production de rhéïne et de diacéréïne par oxydation de l'aloé-émodine, un milieu oxydant achromique permettant d'obtenir la rhéïne et de purifier cette rhéïne. L'acétylation de la rhéïne donnera de la diacéréïne.

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