Process for preparing .alpha.-aryl propionic acids

C - Chemistry – Metallurgy – 07 – C

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260/508.5, 260/5

C07C 57/30 (2006.01) C07C 51/00 (2006.01) C07C 51/377 (2006.01) C07C 59/66 (2006.01)

Patent

CA 1142957

ABSTRACT Process for preparing .alpha.-aryl propionic acids of formula Image (I) in which A is a simple or substituted aryl radical. The process from a methyl-aryl ketone of the formula A-CO-CH3 which is reacted with a compound of formula CHX3, where X is Cl or Br; in the presence of an alkaline hydrate and of a phase transfer catalyst. It forms a mixture of aryl-aliphatic acids Image which is reduced to the compound (I) by means of HI in glacial acetic acid, at 60-70°C. The .alpha.-aryl propionic acids are known compounds.

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