Process for preparing an intermediate for cns depressants

C - Chemistry – Metallurgy – 07 – D

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C07D 498/08 (2006.01) C07D 221/18 (2006.01) C07D 455/03 (2006.01) C07D 498/20 (2006.01)

Patent

CA 1081214

PROCESS FOR PREPARING AN INTERMEDIATE FOR CNS DEPRESSANTS Abstract of the Disclosure Disclosed is a process for preparing (4a,13b-trans)- 1,2,4,4a,8,9,13b,14-octahydro-3H-benzo[6,7]cyclohepta[1,2,3-de]- pyrido[2,1-a]isoquinolin-3-one involving a 1,3-cycloaddition of a 4-halo-1-butene to 1,7,8,12b-tetrahydrobenzo[1,2]cyclohepta- [3,4,5-de]isoquinoline N-oxide. -1-

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