Process for preparing and cultivating haematopoietic...

Details Process for preparing and cultivating haematopoietic... Process for preparing and cultivating haematopoietic...

C - Chemistry, Metallurgy

12

N

C12N 5/00 (2006.01) C12N 5/08 (2006.01) C12N 5/06 (2006.01)

Patent

CA 2170642

Process for the in vitro production of non-immortalised haematopoietic progenitor cells of the erythroid lineage, in which a population of erythroid progenitor cells is exposed to a combination of growth factors containing a glucocorticoid and an oestrogen and at least one ligand of a tyrosine kinase receptor at least until the cells begin to renew themselves.

Procédé de production in vitro de cellules précurseurs hématopoïétiques non immortalisées de la lignée érythrocytaire, selon lequel on expose une population de cellules précurseurs érythrocytaires au moins à une combinaison de facteurs de croissance renfermant un glucocorticoïde et un oestrogène, ainsi qu'au moins un ligand d'un récepteur de tyrosine-kinase, jusqu'à ce que les cellules commencent d'elles-mêmes à se renouveler.

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