Process for preparing and resolving 2-phenyl-3-aminopiperidine

Details Process for preparing and resolving 2-phenyl-3-aminopiperidine Process for preparing and resolving 2-phenyl-3-aminopiperidine

C - Chemistry, Metallurgy

07

D

C07D 211/56 (2006.01)

Patent

CA 2162400

The present invention relates to a novel process for preparing and resolving 3-amino-2-phenylpireridine and for synthesizing from the enantiomers of such compound certain pharmaceutically active substituted 2-phenyl-3-benzylaminopiperidines. The substituted 2-phenyl-3- benzylaminopoperidines that can be prepared by the processes of this invention are substance P receptor antagonists and are useful in the treatment and prevention of inflammatory and central nervous system disorders, as well as several other disorders.

La présente invention se rapporte à un nouveau procédé de préparation et de résolution de 3-amino-2-phénylpipéridine, et de synthèse, à partir des énantiomères de ce composé, de certaines 2-phényl-3-benzylaminopipéridines substituées pharmaceutiquement actives. Les 2-phényl-3-benzylaminopipéridines substituées, qui peuvent être préparées par les procédés de cette invention, sont des antagonistes du récepteur de la substance P et sont utiles dans le traitement et la prévention de troubles inflammatoires et de troubles du système nerveux central ainsi que de plusieurs autres maladies.

Affiliated with

Also associated with

Rating

Process for preparing and resolving 2-phenyl-3-aminopiperidine does not yet have a rating. At this time, there are no reviews or comments for this patent.

If you have personal experience with Process for preparing and resolving 2-phenyl-3-aminopiperidine, we encourage you to share that experience with our LandOfFree.com community. Your opinion is very important and Process for preparing and resolving 2-phenyl-3-aminopiperidine will most certainly appreciate the feedback.

Rate now

Comments { 0 }

Profile ID: LFCA-PAI-O-1695491