Process for preparing aromatic or heteroaromatic sulfonyl...

C - Chemistry – Metallurgy – 07 – C

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C07C 309/86 (2006.01) C07C 303/02 (2006.01) C07C 303/16 (2006.01) C07C 303/18 (2006.01) C07C 315/04 (2006.01) C07C 317/14 (2006.01) C07C 319/20 (2006.01) C07C 323/66 (2006.01) C07D 213/71 (2006.01) C07D 231/18 (2006.01) C07D 241/18 (2006.01) C07D 251/22 (2006.01) C07D 261/10 (2006.01) C07D 263/46 (2006.01) C07D 275/03 (2006.01) C07D 277/36 (2006.01) C07D 307/64 (2006.01) C07D 333/34 (2006.01) C07C 309/89 (2006.01)

Patent

CA 2190256

A process for preparing an aromatic or heteroaromatic sulfonyl halide of the general formula (3): Ar-(-SO2Y)n by halogenating an aromatic or heteroaromatic methyl sulfide of the general formula (1): Ar-(-SCH3-mXm)n or an aromatic or heteroaromatic methyl sulfoxide of the general formula (2): Ar-(-SOCH3-mXm)n with a halogenating agent in the presence of water (wherein Ar is an optionally substituted aromatic or heteroaromatic ring; X and Y are each halogeno; m is an integer of 0 to 3; and n is 1 or 2). This process enables industrial, uncostly and easy production of aromatic or heteroaromatic sulfonyl halides.

L'invention porte sur un procédé permettant de fabriquer un halogénure de soufre aromatique ou hétéroaromatique de la formule générale (3): Ar-(-SO¿2?Y)¿n? par l'halogénation d'un sulfure de méthyle aromatique ou hétéroaromatique de la formule générale (1): Ar-(-SCH¿3-m?X¿m?)¿n? ou d'un sulfoxyde de diméthyle aromatique ou hétéroaromatique de la formule générale (2): Ar-(-SOCH¿3-m?X¿m?)¿n? avec un agent halogénant en présence d'eau. Dans ces formules, Ar est un noyau aromatique ou hétéroaromatique éventuellement substitué, X et Y sont, chacun, halogéno, m représente un nombre entier de 0 à 3 tandis que n vaut 1 ou 2. Ce procédé permet de fabriquer facilement, à peu de frais et industriellement des halogénures de soufre aromatiques ou hétéroaromatiques.

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