Process for preparing arylacetic acid derivatives by...

C - Chemistry – Metallurgy – 07 – C

Patent

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C07C 57/30 (2006.01) B01J 31/24 (2006.01) C07C 51/10 (2006.01) C07C 57/58 (2006.01) C07C 201/12 (2006.01) C07C 205/56 (2006.01) C07C 229/42 (2006.01) C07C 231/12 (2006.01) C07C 235/84 (2006.01) C07C 253/30 (2006.01) C07C 255/57 (2006.01) C07C 303/00 (2006.01) C07C 309/58 (2006.01)

Patent

CA 2148540

The invention relates to a process for preparing aryl- acetic acid derivatives of the formula (I) Image (I) where R1 is hydrogen, halogen, Image , Image , (C1-C8)alkyl, phenyl, which can each also be substituted by hydroxy and amino groups, R2 is hydrogen, (C1-C8)-alkyl, phenyl, and Ar is phenyl, naphthyl, anthracenyl, phenanthrenyl, each of which may be unsubstituted or substituted by halogen, OH, polyfluoro-(C1-C8)-alkyl, CN, (C1-C4)- alkoxy, NO2, COO-(C1-C4)alkyl, CON[(C1-C4)alkyl]2, NH(C1-C4)alkyl, N[(C1-C4)alkyl]2, NH2, SO3H, SO3 ( C1 - C4 ) alkyl, SO2NH2, O-CO-(C1- C4 ) alkyl, CH2-halogen, which comprises carbonylating compounds of the formula (II) Image ( I I ) where Ar and R1 have the meanings given above and Halogen is I, Br, Cl, using a water-soluble metal complex as catalyst in a two-phase system.

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