C - Chemistry – Metallurgy – 07 – D
Patent
C - Chemistry, Metallurgy
07
D
C07D 403/02 (2006.01)
Patent
CA 2612419
Provided are methods for the synthesis of heterocyclic compounds such as benzimidazole carboxylic acid core structures having Formula Ia-1 and their synthetic intermediates: wherein Z, X1, X2, X5, R2 and R10 are as defined herein. Compounds of Formula Ia-1 and their synthetic intermediates can be used to prepare heterocyclic derivatives such as benzimidazole derivatives.
Procédés pour la synthèse de composés hétérocycliques du type structures centrales d'acide benzimidazole-carboxylique de formule Ia-1 et leurs intermédiaires synthétiques, sachant que Z, X1, X2, X5, R2 et R10 sont tels que définis dans la description. Les composés et intermédiaires décrits peuvent être utilisés pour l'élaboration de dérivés hétérocycliques du type dérivés benzimidazole.
Demattei John
Evans Matthew Charles
Ford James Gair
Hache Bruno P.
Leonard John
Array Biopharma Inc.
Astrazeneca Ab
Gowling Lafleur Henderson Llp
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