Process for preparing benzo¬b|thiophenes

Details Process for preparing benzo¬b|thiophenes Process for preparing benzo¬b|thiophenes

C - Chemistry, Metallurgy

07

D

C07D 333/58 (2006.01) C07D 333/56 (2006.01) C07D 409/12 (2006.01)

Patent

CA 2236254

The preparation of benzo[b]thiophenes by the acylation of alkoxy protected starting materials followed by demethylation using essentially odorless thiol compounds are provided herewith. Demethylation may be carried out in the same reaction vessel without isolation of the acylated, protected material.

L'invention porte sur la préparation de benzo¢b!thiophènes par acylation de matières de départ protégées par un alcoxy, suivie d'une déméthylation à l'aide de composés de type thiol pratiquement inodores. La déméthylation peut être effectuée dans la même cuve de réaction sans isoler la matière acylée, protégée.

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