Process for preparing benzo¬c|phenanthridinium derivatives,...

Details Process for preparing benzo¬c|phenanthridinium derivatives,... Process for preparing benzo¬c|phenanthridinium derivatives,...

C - Chemistry, Metallurgy

07

D

C07D 221/18 (2006.01) A61K 31/47 (2006.01) C07D 491/04 (2006.01) C07D 491/056 (2006.01)

Patent

CA 2054569

ABSTRACT OF THE DISCLOSURE The present invention relates to a process for preparing benzo[c]phenanthridinium derivatives of the general formula A: Image (A) wherein M and N individually represent a hydroxyl or lower alkoxy group, or M and N simultaneously represent a hydrogen atom or together form a methylenedioxy group, X- represents an acid residue or a hydrogen acid residue, and R represents a lower alkyl group. This process has good reproducibility and may be effected under moderate conditions, and therefore the process is practically useful. Also, it has been found that certain novel benzo[c]phenanthridinium derivatives, prepared by the present process, have not only an antitumor activity but also an inhibition activity on blood platelet aggregation. In addition, hydrogen salts of the present compounds have an enhanced stability, which is an advantage in formulating into phamaceutical preparations.

Affiliated with

Also associated with

Rating

Process for preparing benzo¬c|phenanthridinium derivatives,... does not yet have a rating. At this time, there are no reviews or comments for this patent.

If you have personal experience with Process for preparing benzo¬c|phenanthridinium derivatives,..., we encourage you to share that experience with our LandOfFree.com community. Your opinion is very important and Process for preparing benzo¬c|phenanthridinium derivatives,... will most certainly appreciate the feedback.

Rate now

Comments { 0 }

Profile ID: LFCA-PAI-O-2059825