Process for preparing boronic acids and esters in the...

C - Chemistry – Metallurgy – 07 – F

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C07F 5/02 (2006.01) C07F 5/04 (2006.01)

Patent

CA 2741514

The present invention relates to the process for preparing a boronic acid or ester chemically, in which an aromatic compound is reacted with a boronating agent, in the presence of magnesium metal (Mg0). The invention also relates to the boronic acids or esters that can be obtained by means of this process and to the use thereof for example as a synthesis intermediate, in the Suzuki reaction, in the pharmaceutical or alternatively electronics field.

La présente invention se rapporte au procédé de préparation d'un acide ou d'un ester boronique par voie chimique dans lequel on fait réagir avec un composé aromatique avec un agent de boration, en présence de magnésium métallique (Mg0). L'invention concerne également les acides ou esters boroniques susceptibles d'être obtenus par ce procédé et leur utilisation par exemple comme intermédiaire de synthèse, dans la réaction de Suzuki, dans le domaine pharmaceutique ou encore électronique.

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