Process for preparing bosentan

C - Chemistry – Metallurgy – 07 – D

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C07D 239/52 (2006.01) C07D 239/69 (2006.01)

Patent

CA 2712860

The present invention relates to a novel intermediate useful in the preparation of bosentan and to processes for the preparation of said intermediate and bosentan. The invention further relates to compositions comprising bosentan prepared according to the processes of the invention and their use in the treatment of endothelin-receptor mediated disorders.

La présente invention porte sur un nouvel intermédiaire utile dans la préparation de bosentan et sur des procédés de préparation dudit intermédiaire et dudit bosentan. L'invention porte également sur des compositions contenant du bosentan préparé conformément aux procédés de l'invention et sur leur utilisation dans le traitement de troubles à médiation par le récepteur des endothélines.

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