C - Chemistry – Metallurgy – 07 – D
Patent
C - Chemistry, Metallurgy
07
D
C07D 307/78 (2006.01) C07C 49/293 (2006.01) C07C 49/327 (2006.01) C07C 61/04 (2006.01) C07D 211/70 (2006.01) C07D 231/10 (2006.01) C07D 233/54 (2006.01) C07D 307/16 (2006.01) C07D 307/22 (2006.01) C07D 307/24 (2006.01) C07D 307/79 (2006.01) C07D 307/80 (2006.01) C07D 307/81 (2006.01) C07D 307/87 (2006.01)
Patent
CA 2374627
A process is provided for preparing chiral cyclopropane carboxylic acids, preferably of structure (I) which are intermediates used in preparing acyl guanidine sodium/proton exchange (NHE) inhibitors.
Cette invention concerne un procédé de préparation d'acides carboxyliques cyclopropane chiraux, de préférence de structure (I), qui font office d'intermédiaires dans la fabrication d'inhibiteurs d'échange sodium-protons à base de guanidines d'acyle.
Ahmad Saleem
Atwal Karnail
Chen Bang-Chi
Dugar Sundeep
North Jeffrey T.
Bristol-Myers Squibb Company
Gowling Lafleur Henderson Llp
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