Process for preparing depolymerized and supersulfated heparin

Details Process for preparing depolymerized and supersulfated heparin Process for preparing depolymerized and supersulfated heparin

C - Chemistry, Metallurgy

08

B

260/226

C08B 37/10 (2006.01) C08B 37/00 (2006.01)

Patent

CA 1210760

ABSTRACT OF THE DISCLOSURE Process for the preparation of depolymerized and supersulfated heparin having a molecular weight comprised between 2000 and 9000 and a sulfatation degree of at least 2.5, in which all of the primary hydroxy groups are sulfated, said process comprising the steps of reacting a heparin of natural origin, or a fraction thereof, with a sulfuric acid/chloro-sulfonic acid mixture.

443860

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