Process for preparing dihydrofuranone derivatives

C - Chemistry – Metallurgy – 07 – D

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C07D 307/33 (2006.01)

Patent

CA 2041813

ABSTRACT The present invention provides a process for preparing dihydrofuranone derivative of the formula (II): Image (II) wherein R1 and R3 are individually lower alkyl, and R2 is hydrogen or lower alkyl, by reacting a dihydrofuranone derivative of the formula (I): Image (I) wherein R1 is as defined above, with a malonic acid derivative of the formula (II): Image (II) wherein R2 and R3 are as defined above, in the presence of an alkalimetal alkoxide and/or an alkalimetal hydroxide.

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