Process for preparing doxorubicin

Details Process for preparing doxorubicin Process for preparing doxorubicin

C - Chemistry, Metallurgy

12

N

C12N 15/53 (2006.01) C12N 9/02 (2006.01) C12P 19/56 (2006.01)

Patent

CA 2188571

The ability to convert daunorubicin to doxorubicin can be conferred on a host cell by transformation with a recombinant vector comprising DNA encoding daunorubicin 14-hydroxylase. The host cell can then be used to produce doxorubicin.

Il est possible de conférer à une cellule hôte l'aptitude à convertir la daunorubicine en doxorubicine par transformation de cette dernière avec un vecteur recombinant comprenant de l'ADN codant la daunorubicine 14-hydroxylase. Cette cellule hôte peut alors être utilisée pour produire de la doxorubicine.

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