Process for preparing enantiomerically enriched...

Details Process for preparing enantiomerically enriched... Process for preparing enantiomerically enriched...

C - Chemistry, Metallurgy

12

P

C12P 41/00 (2006.01) C07D 209/52 (2006.01) C12P 13/00 (2006.01)

Patent

CA 2295017

The present invention relates to a process for the production of substantially enantiomerically pure intermediates of formula (IV), wherein P is an activating and protecting group, from their racemates by treating the mixture with an acylase enzyme derived from Bacillus sp..

La présente invention concerne un procédé de production de produits intermédiaires sensiblement purs du point de vue des énantiomères, qui sont représentés par la formule (IV) dans laquelle P est un groupe d'activation et de protection. On obtient ces produits intermédiaires à partir de leurs composés racémiques en traitant le mélange au moyen d'une enzyme acylase provenant de Bacillus sp..

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