C - Chemistry – Metallurgy – 07 – D
Patent
C - Chemistry, Metallurgy
07
D
C07D 487/06 (2006.01) C07C 233/36 (2006.01) C07C 311/18 (2006.01) C07D 233/36 (2006.01) C07D 311/00 (2006.01)
Patent
CA 2117197
2117197 9306106 PCTABS00021 Process for preparing enantiomerically pure imidazo[4,5,1-jk][1,4]benzodiazepin-2(1H^_)-thiones of formula (I), starting from 2,6-dihalo-3-nitrobenzyl derivatives (II) and suitably N^_-protected 1,2-diaminopropanes (III). Novel enantiomerically pure intermediates of formulas (III) and (IV) prepared in the course of the present process.
de Knaep Alfons G. M.
Moens Luc J. R.
Vreysen Eduard J. C.
Gowling Lafleur Henderson Llp
Janssen Pharmaceutica Naamloze Vennootschap
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