C - Chemistry – Metallurgy – 07 – C
Patent
C - Chemistry, Metallurgy
07
C
260/472.3
C07C 69/612 (2006.01) C07C 43/303 (2006.01) C07C 43/315 (2006.01) C07C 45/63 (2006.01) C07C 51/00 (2006.01) C07C 59/64 (2006.01) C07D 209/48 (2006.01) C07D 317/16 (2006.01) C07D 317/22 (2006.01) C07D 317/28 (2006.01) C07D 319/06 (2006.01) C07D 333/22 (2006.01)
Patent
CA 1196010
ABSTRACT OF THE DISCLOSURE Process for preparing esters of 2-(6'-methoxy-2'-naphtyl)- propionic acid via rearrangement of new ketals of 2-halo-1-(6'- methoxy-2'-naphtyl)-propan-1-one in the presence of a Lewis acid. The esters thus obtained are useful as intermediate products for preparing Naproxen.* The process involves the preparation of the following new compounds: ketals of 2-halo-1-(6'-methoxy-2'- naphtyl)-propan-1-one; esters of 2-(5'-bromo-6'-methoxy-2'- naphtyl)-propionic acid; 1-(5'-bromo-6'-methoxy-2'-naphtyl)- propan-1-one; 2-halo (5'-bromo-6'-methoxy-2'-naphtyl)-propan-1-one. *Trade Mark
371692
Belli Aldo
Giordano Claudio
Uggeri Fulvio
Villa Giovanni
Blaschim S.p.a.
George H. Riches And Associates
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