Process for preparing galanthamine derivatives by asymmetric...

Details Process for preparing galanthamine derivatives by asymmetric... Process for preparing galanthamine derivatives by asymmetric...

C - Chemistry, Metallurgy

07

D

C07D 491/06 (2006.01) C07D 491/10 (2006.01)

Patent

CA 2215518

A process for preparing a compound of formula (3) in enantio-enriched form, comprises reducing a compound of formula (4) using an asymmetric enantiospecific reductant, wherein A1 = A2 = H or A1, A2 = O; B1 = B2 = H or B1, B2 = O; Z = H, C1-20 alkyl or a precursor thereof, or a removable protecting group for nitrogen, e.g. acyl or alkyloxycarbonyl; Y = H or a substituent; R1 = C1-20 alkyl; and R is an optional, additional substituent.

Un procédé de préparation d'un composé de formule (3) sous une forme énantio-enrichie, consiste en la réduction d'un composé de formule (4) au moyen d'un réducteur asymétrique spécifique à l'isométrie optique, dans lequel A<1> = A<2> = H ou A<1>, A<2> = 0; B<1> = B<2> = H ou B<1>, B<2> = O; Z = H, alkyle C1-20 ou un des ses précurseurs, ou un groupe de protection séparable pour l'azote, par exemple acyle ou alkyloxycarbonyle; Y = H ou un substituent; R<1> = alkyle C1-20; et R est un substituent facultatif et additionnel.

Affiliated with

Also associated with

Rating

Process for preparing galanthamine derivatives by asymmetric... does not yet have a rating. At this time, there are no reviews or comments for this patent.

If you have personal experience with Process for preparing galanthamine derivatives by asymmetric..., we encourage you to share that experience with our LandOfFree.com community. Your opinion is very important and Process for preparing galanthamine derivatives by asymmetric... will most certainly appreciate the feedback.

Rate now

Comments { 0 }

Profile ID: LFCA-PAI-O-1629293