Process for preparing hepatitis b surface antigen containing...

Details Process for preparing hepatitis b surface antigen containing... Process for preparing hepatitis b surface antigen containing...

A - Human Necessities

61

K

167/130

A61K 39/29 (2006.01) A61L 2/00 (2006.01)

Patent

CA 1265448

ABSTRACT OF THE DISCLOSURE There is disclosed a process for producing a proteinaceous mass containing particles of HBsAg in a morphological form not found in nature while inactivating any live virus contained therein. The process comprises subjecting a concentrated mass thereof free of protein diluent or a stabilizer to a heat inactivation by heating the same while in a concentration of at least 1 mg/ml at a temperature of 101 to 105°C for 1 to 15 minutes and thereafter cooling the so heated particles.

505499

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