Process for preparing indoleacetic acid ester derivatives

C - Chemistry – Metallurgy – 07 – D

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260/207.1

C07D 209/26 (2006.01) C07D 209/28 (2006.01)

Patent

CA 1069889

ABSTRACT OF THE DISCLOSURE The present invention relates to the processes for preparing indoleacetic acid ester derivatives of the following general formula : Image wherein n represents an integer from one to 3 ; R is selected from the group consisting of hydroxyl, halogen, trihalomethyl, alkoxy, acyloxy, substituted phenyl, pyridyl and substituted pyridyl. The compounds of the present invention possess a high degree of pharmacological activities such as analgetic, anti-inflammatory and anti-pyretic activities as well as low side effects on the gastrointestinal tracts when given orally and topically, and therefore they may be useful as analgesics, anti-inflammatories and anti-pyretics for internal and external use.

279880

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