Process for preparing isoindolin derivatives

Details Process for preparing isoindolin derivatives Process for preparing isoindolin derivatives

C - Chemistry, Metallurgy

07

D

260/321

C07D 209/46 (2006.01)

Patent

CA 1155448

NOVEL PROCESS FOR PREPARING ISOINDOLIN DERIVATIVES Abstract of the disclosure: A process for the preparation of an isoindolin derivative comprising cyclizing a benzylidene derivative in the presence of a reducing agent such as sodium boron hydride. In one embodiment, the benzylidene derivative may be substi- tuted by a reaction mixture containing the same, the reaction mixture being prepared by reacting o-phthalaldehydic acid or its ester with an aniline derivative.

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