Process for preparing l-nucleic acid derivatives and...

Details Process for preparing l-nucleic acid derivatives and... Process for preparing l-nucleic acid derivatives and...

C - Chemistry, Metallurgy

07

H

C07H 19/073 (2006.01)

Patent

CA 2643748

A novel method has been found to produce 2,2'-anhydro-1-(.beta.-L- arabinofuranosyl)thymine as a novel useful intermediate compound. A novel method has been further found to produce thymidine from 2,2'-anhydro-1- (.beta.-L-arabinofuranosyl)thymine. According to these methods, synthesis of various L- nucleic acid derivatives, synthesis of which has been difficult till now.

La présente invention concerne une nouvelle méthode d'obtention de 2,2'-anhydro-1-(.beta.-L-arabinofuranosyl)thymine, un nouveau composé intermédiaire utile. La présente invention concerne également une nouvelle méthode d'obtention de la thymidine à partir de 2,2'-anhydro-1-(.beta.-L-arabinofuranosyl)thymine. Selon ces méthodes, il est possible de synthétiser divers dérivés d'acides L-nucléiques, ce qui était jusqu'à présent difficile.

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