Process for preparing lysergol derivatives

C - Chemistry – Metallurgy – 07 – D

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204/91.17, 260/2

C07D 457/02 (2006.01)

Patent

CA 1124713

ABSTRACT A novel process is disclosed for the preparation of derivatives of lysergol having the general formula: Image According to this process lysergol is directly used as the starting compound and, after the methylation at the 1 position of corresponding 10 alpha-methoxy-lumilysergol, the methy- lated compound is directly esterfied with a carboxylic acid R-COOH, the acid being selected in the group comprising aliphatic, cyclo- aliphatic, aromatic, and heterocyclic carboxylic acids, containing up to 10 carbon atoms.

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