C - Chemistry – Metallurgy – 07 – K
Patent
C - Chemistry, Metallurgy
07
K
530/5.06
C07K 5/06 (2006.01) C07K 5/02 (2006.01)
Patent
CA 1329445
Abstract of the Disclosure A process for preparing N-[1(S)-ethoxycarbonyl- 3-phenylpropyl]-L-alanyl-L-proline, which comprises reacting N-carboxyanhydride of N-[1(S)-ethoxycarbonyl- 3-phenylpropyl]-L-alanine with L-proline in the presence of a base. According to the process, enalapril can be prepared economically, easily and effectively.
516505
Inoue Kenji
Ohashi Takehisa
Takahashi Satomi
Watanabe Kiyoshi
Yanagida Yoshifumi
Kanegafuchi Kagaku Kogyo Kabushiki Kaisha
Osler Hoskin & Harcourt Llp
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